For clinicians and researchers

The research behind the briefs

The parent-facing briefs are short by design. This is the working layer underneath them: what the published literature actually supports, and how reliably.

A reading of the published literature, not a clinical guideline. Every claim below is sourced, and each source is marked with how it was actually obtained — a claim resting on an abstract alone says so. Treatment decisions belong to the clinician in front of the patient.

Building an SSPE registry, and the route through regulation

The one deliverable that needs no drug, no device and no new science — and what Pakistani law actually requires.

Draft 02

Every source, and how each one was obtained

All 85 documents behind this research, each tagged by whether the full text was read or only the abstract could be got.

Reference

On the untried combinations

This research also sets out several treatment combinations that have never been tried together. Those are deliberately not published here. They are hypothesis-generating, they would need ethics approval before anyone acted on them, and an open web page is read by families as readily as by clinicians. Clinicians and researchers can request that part of the work.